产品货号：
Z22939
中文名称：
PAK6抗体
英文名称：
Anti-PAK6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAK6 Antibody |
| 指标别名 | p21 activated kinase 6;PAK 6;PAK6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PAK6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human PAK6(16-32aa QNFQHRVHTSFDPKEGK),identical to the related rat and mouse sequences. |
| 实际分子量 | 75KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Serine/threonine-protein kinase PAK 6(p21 Protein-activated Kinase 6) is an enzyme that in humans is encoded by the PAK6 gene.The PAK6 gene is mapped to chromosome 15q15.based on an alignment of the PAK6 sequence with the genomic sequence.This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase(PAK) family members.The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases,characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding(CRIB) domain and a carboxyl-terminal kinase domain.PAK kinases are implicated in the regulation of a number of cellular processes,including cytoskeleton rearrangement,apoptosis and the MAP kinase signaling pathway.The protein encoded by this gene was found to interact with androgen receptor(AR),which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. |
| Uniprot ID | Q9NQU5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | p21 protein(Cdc42/Rac)-activated kinase 6 |
| 蛋白名全称 | Serine/threonine-protein kinase PAK 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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